To live and learn: Making memories has to be a speedy business

Public release date: 15-Oct-2013
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Contact: Anita Kar
anita.kar@mcgill.ca
514-398-3376
McGill University

This news release is available in French.

The brain is plastic - adapting to the hundreds of experiences in our daily lives by reorganizing pathways and making new connections between nerve cells. This plasticity requires that memories of new information and experiences are formed fast. So fast that the body has a special mechanism, unique to nerve cells, that enables memories to be made rapidly. In a new study from The Montreal Neurological Institute and Hospital, The Neuro, McGill University with colleagues at the Universit de Montral, researchers have discovered that nerve cells have a special 'pre-assembly' technique to expedite the manufacture of proteins at nerve cell connections (synapses), enabling the brain to rapidly form memories and be plastic.

Making a memory requires the production of proteins at synapses. These proteins then change the strength of the connection or pathway. In nerve cells the production process for memory proteins is already pre-assembled at the synapse but stalled just before completion, awaiting the proper signals to finish, thereby speeding up the entire process. When it comes time to making the memory, the process is switched on and the protein is made in a flash. The mechanism is analogous to a pre-fab home, or pre-made pancake batter that is assembled in advance and then quickly completed in the correct location at the correct time.

"It's not only important to make proteins in the right place but, it's also important not to make the protein when it's the wrong time," says Dr. Wayne Sossin, neuroscientist at The Neuro and senior investigator on the paper. "This is especially important with nerve cells in the brain, as you only want the brain to make precise connections. If this process is indiscriminate, it leads to neurological disease. This mechanism to control memory protein synthesis solves two problems: 1) how to make proteins only at the right time and 2) how to make proteins as quickly as possible in order to tightly associate the synaptic change with the experience/memory.

Making proteins from genetic material involves two major steps [a Nobel prize was awarded for the identification of the cell's protein-making process]. In the first step, called transcription, the information in DNA that is stored and protected within the centre of the cell is copied to a messenger RNA (mRNA) this copy is then moved to where it is needed in the cell. In the second step, called translation, the mRNA is used as a template of genetic information and 'read' by little machines called ribosomes, which decode the mRNA sequence and stitch together the correct amino acids to form the protein.

Dr. Sossin's group at The Neuro has discovered that the mRNA travels to the synapse already attached to the ribosome, with the protein production process stopped just before completion of the product (at the elongation/termination step of translation, where amino acids are being assembled into protein). The 'pre-assembly' process then waits for synaptic signals before re-activating to produce a lot of proteins quickly in order to form a memory. "Our results reveal a new mechanism underlying translation-dependent synaptic plasticity, which is dysregulated in neurodevelopmental and psychiatric pathologies", added Dr. Sossin. "Understanding the pathways involved may provide new therapeutic targets for neurodevelopmental disorders. "

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The Neuro

The Montreal Neurological Institute and Hospital The Neuro, is a unique academic medical centre dedicated to neuroscience. Founded in 1934 by the renowned Dr. Wilder Penfield, The Neuro is recognized internationally for integrating research, compassionate patient care and advanced training, all key to advances in science and medicine. The Neuro is a research and teaching institute of McGill University and forms the basis for the Neuroscience Mission of the McGill University Health Centre. Neuro researchers are world leaders in cellular and molecular neuroscience, brain imaging, cognitive neuroscience and the study and treatment of epilepsy, multiple sclerosis and neuromuscular disorders. For more information, visit theneuro.com.

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 15-Oct-2013
[


| E-mail



| Share

]

Contact: Anita Kar
anita.kar@mcgill.ca
514-398-3376
McGill University

This news release is available in French.

The brain is plastic - adapting to the hundreds of experiences in our daily lives by reorganizing pathways and making new connections between nerve cells. This plasticity requires that memories of new information and experiences are formed fast. So fast that the body has a special mechanism, unique to nerve cells, that enables memories to be made rapidly. In a new study from The Montreal Neurological Institute and Hospital, The Neuro, McGill University with colleagues at the Universit de Montral, researchers have discovered that nerve cells have a special 'pre-assembly' technique to expedite the manufacture of proteins at nerve cell connections (synapses), enabling the brain to rapidly form memories and be plastic.

Making a memory requires the production of proteins at synapses. These proteins then change the strength of the connection or pathway. In nerve cells the production process for memory proteins is already pre-assembled at the synapse but stalled just before completion, awaiting the proper signals to finish, thereby speeding up the entire process. When it comes time to making the memory, the process is switched on and the protein is made in a flash. The mechanism is analogous to a pre-fab home, or pre-made pancake batter that is assembled in advance and then quickly completed in the correct location at the correct time.

"It's not only important to make proteins in the right place but, it's also important not to make the protein when it's the wrong time," says Dr. Wayne Sossin, neuroscientist at The Neuro and senior investigator on the paper. "This is especially important with nerve cells in the brain, as you only want the brain to make precise connections. If this process is indiscriminate, it leads to neurological disease. This mechanism to control memory protein synthesis solves two problems: 1) how to make proteins only at the right time and 2) how to make proteins as quickly as possible in order to tightly associate the synaptic change with the experience/memory.

Making proteins from genetic material involves two major steps [a Nobel prize was awarded for the identification of the cell's protein-making process]. In the first step, called transcription, the information in DNA that is stored and protected within the centre of the cell is copied to a messenger RNA (mRNA) this copy is then moved to where it is needed in the cell. In the second step, called translation, the mRNA is used as a template of genetic information and 'read' by little machines called ribosomes, which decode the mRNA sequence and stitch together the correct amino acids to form the protein.

Dr. Sossin's group at The Neuro has discovered that the mRNA travels to the synapse already attached to the ribosome, with the protein production process stopped just before completion of the product (at the elongation/termination step of translation, where amino acids are being assembled into protein). The 'pre-assembly' process then waits for synaptic signals before re-activating to produce a lot of proteins quickly in order to form a memory. "Our results reveal a new mechanism underlying translation-dependent synaptic plasticity, which is dysregulated in neurodevelopmental and psychiatric pathologies", added Dr. Sossin. "Understanding the pathways involved may provide new therapeutic targets for neurodevelopmental disorders. "

###

The Neuro

The Montreal Neurological Institute and Hospital The Neuro, is a unique academic medical centre dedicated to neuroscience. Founded in 1934 by the renowned Dr. Wilder Penfield, The Neuro is recognized internationally for integrating research, compassionate patient care and advanced training, all key to advances in science and medicine. The Neuro is a research and teaching institute of McGill University and forms the basis for the Neuroscience Mission of the McGill University Health Centre. Neuro researchers are world leaders in cellular and molecular neuroscience, brain imaging, cognitive neuroscience and the study and treatment of epilepsy, multiple sclerosis and neuromuscular disorders. For more information, visit theneuro.com.

---

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-10/mu-tla101513.php
Category: Marquez vs Bradley   remembering 9/11   2020 Olympics   Samsung   paulina gretzky  

Les News, 101513

Mikhail Stands Up, Sly's Costly Autograph, Tina & Amy FTW!

Posted by: Trent on October 15, 2013|

• • Concert poster artwork is a underappreciated artform. [Buzzfeed]


• • A story of high school love. [Queerty]


• • Josh Hutcherson covers Seventeen magazine. [PopSugar]


• • Kate Winslet covers Vogue magazine. [GossipCop]


• • Mikhail Baryshnikov stands up for gay people in Russia. [Towleroad]


• • Cartier sells more than just for diamonds. [Oh La La]


• • Sylvester Stallone charges almost $400 for an autograph. [Newser]


• • Apple is gettin’ ready to unveil their new iPads. [Heavy]


• • Angel Haze puts her spin on Kanye West‘s Black Skinhead. [Idolator]


• • Have you met Max and the Moon? [arjanwrites]


• • Tina Fey and Amy Poehler will host the Golden Globes for the next two years. [Starpulse]


• • Oh gods, make it stop. [Global Grind]


• • Charlie Hunnam doing what he does best. [LaineyGossip]


• • Keyshia Cole is 32, Ginuwine is 43, Emeril Lagasse is 54, Tito Jackson is 60, Penny Marshall is 70 and Linda Lavin (Alice) is 76 years old. Click HERE to see who else is celebrating a birthday

Source: http://feedproxy.google.com/~r/pinkisthenewblog/~3/H3GU3MUaU5Y/les-news-101513
Tags: james spader   liberace  

Shutdown impact: Some national parks could reopen

The government shutdown continues with some glimmer of hope for those who would like to visit the nation's national parks: The Obama administration said it would consider offers from the states to use their own money to pay for park operations and Utah jumped at the chance.

The shutdown has had far-reaching consequences for some but minimal impact on others. Mail is being delivered. Social Security and Medicare benefits continue to flow. But the shutdown has been particularly harsh on those who rely on tourism, such as communities near the Grand Canyon and Yellowstone national parks.

A look at how services have been affected, and sometimes not, by Congress failing to reach an agreement averting a partial government shutdown:

TRAVEL

Federal air traffic controllers remain on the job and airport screeners continue to funnel passengers through security checkpoints. Furloughs of safety inspectors had put inspections of planes, pilots and aircraft repair stations on hold, but the Federal Aviation Administration says it is asking 800 employees — including some safety inspectors — to return to work this week. More than 2,900 inspectors had been furloughed. The State Department continues processing foreign applications for visas and U.S. applications for passports, since fees are collected to finance those services. Embassies and consulates overseas remain open and are providing services for U.S. citizens abroad.

BENEFIT PAYMENTS

Social Security and Medicare benefits continue to be paid out, but there could be delays in processing new disability applications. The Social Security Administration is also delaying the announcement of the size of next year's cost-of-living adjustment, which was supposed to come out on Oct. 16. Unemployment benefits are also still going out.

FEDERAL COURTS

Federal courts, which have been using fees and other funds to operate since the shutdown began, will likely have enough money to operate until Oct. 17, and possibly Oct. 18.

After that, the courts will run out of money and shut down all nonessential work.

A limited number of workers would perform essential work, while all others would be furloughed. Each court would make a determination on what is essential and nonessential. Judges would still be able to seat jurors, but the jurors won't be paid until Congress provides funding. Court-appointed lawyers would also not get paid.

The Supreme Court opened its term Monday and says its business will go on despite the ongoing shutdown. The Supreme Court announced Thursday it would stay open through Friday, Oct. 18, including hearing two days of arguments next week.

RECREATION

All national parks have been closed since the shutdown began, but the Obama administration said Thursday it would allow states to use their own money to reopen some national parks.

Utah is the first state to take up the offer, and national parks located there are expected to open Saturday. Colorado also reached agreement to reopen Rocky Mountain National Park. But several states say they are unlikely to participate.

Figures compiled by a coalition of retired park service workers indicate that some 700,000 people a day would have been visiting the parks and that the surrounding areas are losing $76 million in visitor spending per day.

In Washington, monuments along the National Mall have been closed, as have the Smithsonian museums, including the National Zoo. Among the visitor centers that have closed: the Statue of Liberty in New York, Independence Hall in Philadelphia and Alcatraz Island near San Francisco.

National wildlife refuges were closed to hunters and fishermen just as hunting season was getting underway in many states. However, the Fish and Wildlife Service said late Friday that it's reopening several wildlife refuges, mostly in the Midwest, to allow pheasant and duck hunting.

CONSUMER SAFETY

Several protection agencies have curtailed their work.

The Nuclear Regulatory Commission shut down most operations on Thursday. However, resident inspectors will remain on the job and any immediate safety or security matters will be handled.

The Food and Drug Administration and Centers for Disease Control and Prevention say they can handle recalls and high-risk foodborne outbreaks, but discovering them will be more difficult because many of the people who investigate outbreaks have been furloughed. Routine food safety inspections were suspended, so most food manufacturers won't have to worry about periodic visits from government inspectors. U.S. food inspections abroad have also been halted. USDA inspectors are on the lines every day in meatpacking plants and are required to be there by law for the plants to stay open.

The National Transportation Safety Board is not investigating most transportation accidents, making an exception only if officials believe lives or property are in danger. The agency suspended 1,500 investigations that were underway before the shutdown. Nor has the board collected information on or sent investigators to the scene of 20 accidents involving U.S.-manufactured aircraft that have occurred around the globe since Sept. 30.

Auto recalls and investigations of safety defects have been put on hold during the partial government shutdown. The public can still file safety complaints through the National Highway Traffic Safety Administration's website, but no one has been investigating them in the new fiscal year. Manufacturers can still voluntarily recall vehicles, but major recalls are typically negotiated between the government and automakers.

The Consumer Product Safety Commission is no longer screening products at ports of entry to prevent potentially dangerous ones from reaching store shelves, such as children's products containing excessive levels of lead.

ENVIRONMENT

At the Environmental Protection Agency, the shutdown means the agency can no longer certify whether vehicles meet emissions standards, delaying some new models from reaching car lots. New pesticides and industrial chemicals are also in limbo because the EPA has halted reviews of their health and environmental effects. And the nation's environmental police are no longer checking to see if polluters are complying with agreements to reduce their pollution.

HEALTH

New patients are generally not being accepted into clinical research at the National Institutes of Health, but current patients continue to receive care. NIH has made exceptions to allow 12 patients with immediately life-threatening illnesses — mostly cancer — into research studies at its renowned hospital. Normally, about 200 new patients every week enroll in studies at the NIH's research-only hospital, many of them after standard treatments have failed. Medical research at the NIH has been disrupted as some studies have been delayed. The Centers for Disease Control and Prevention has been severely limited in spotting or investigating disease outbreaks such as the flu or that mysterious MERS virus from the Middle East. The FDA has halted the review and approval of new medical products and drugs.

EDUCATION

The impact of the shutdown on school districts, colleges and universities has been relatively minimal. Student loans have continued to be paid out. But school trips to national parks and museums have been canceled, and some university researchers have been unable to apply for grants or access government databases. Vocational rehabilitation programs helping adults with disabilities could begin to feel a pinch because these agencies receive 80 percent of their funding from the federal government.

LABOR ISSUES

The Equal Employment Opportunity Commission will not investigate any charges of discrimination or respond to questions from the public during the shutdown. It will request delays in ongoing court proceedings and will not hold any hearings or mediations. The National Labor Relations Board, which investigates and remedies unfair labor practices, has virtually ceased to exist during the shutdown. More than 99 percent of its staff has been furloughed, postponing nearly every pending hearing, investigation and union election.

TAXES

The Internal Revenue Service says more than 12 million taxpayers who filed for automatic extensions in the spring have tax returns due on Tuesday. Those returns, the agency says, are still due, regardless of the shutdown.

The IRS suspended all audits and will not be processing any tax refunds during the shutdown. Got questions? Sorry, IRS call centers will not be staffed, though automated lines are still running.

ECONOMIC DATA

How well is the economy faring? That's harder to tell given the array of economic reports measuring the health of the nation's economy that have been postponed. The reports measure such things as monthly unemployment, inflation, imports and exports, and retail sales.

HOUSING

Some borrowers are finding it harder to close on their mortgages. The delays could worsen if the shutdown continues and possibly undercut the nation's housing recovery. Some lenders are having trouble confirming applicants' income tax returns and Social Security data due to government agency closures. Furloughs at the Federal Housing Administration are slowing the agency's processing of loans for some low- to moderate-income borrowers and first-time homebuyers. About 15 percent of new loans for home purchases are insured by the FHA. The Department of Housing and Urban Development won't be able to provide any additional payments to the nation's 3,300 public housing authorities during the shutdown, but those authorities should have enough money to continue providing rental assistance through the end of December.

WEATHER

The National Weather Service is forecasting weather and issuing warnings while the National Hurricane Center continues to track storms. The scientific work of the U.S. Geological Survey has been halted.

LAW ENFORCEMENT

The FBI estimates that about 80 percent of its 35,000 employees are working and says it is prepared to meet any immediate threats. However, activities are suspended for other, longer-term investigations of crimes. Training and other support functions have been slashed.

MILITARY

The military's 1.4 million active-duty personnel remain on duty. About half of the Defense Department's civilian employees were furloughed, but Defense Secretary Chuck Hagel ordered nearly all 350,000 back on the job. Congress has ensured $100,000 payments to families of fallen service members would continue, passing a bill signed by President Barack Obama on Thursday. The payments had been suspended during the shutdown, prompting the Fisher House Foundation to volunteer to make the payments until the program got up and running again.

The military has also stopped providing tuition assistance for service members taking college courses during off-duty hours.

VETERANS SERVICES

Veterans are still able to get inpatient care at hospitals and mental health counseling at vet centers and outpatient clinics because Congress approved funding for VA health care programs one year in advance. Operators are also staffing the crisis hotline. The VA says its efforts to reduce the backlog in disability benefit claims have been stalled because claims processors are no longer being required to work 20 hours of overtime per month. Access to regional VA offices has been suspended, making it harder for veterans to get information about their benefits and the status of their claims. If the shutdown continues into late October, the VA warns that compensation and pension payments to veterans will be halted.

NATIONAL SECURITY

The CIA furloughed a "significant" but undisclosed number of workers when the shutdown began. A week later, CIA Director John Brennan said he would begin bringing back employees deemed necessary to the CIA's core missions of foreign intelligence collection, analysis, covert action and counterintelligence. He said continuing dramatically reduced staffing levels posed a threat to the safety of human life and the protection of property.

___

Associated Press writers Kevin Freking, Sam Hananel, Joan Lowy, Matthew Daly, Frederic J. Frommer, Andrew Miga, Hope Yen, Deb Riechmann, Lauran Neergaard, Dina Cappiello, Pete Yost, Stephen Ohlemacher, Lolita C. Baldor, Jesse J. Holland, Seth Borenstein, Mary Clare Jalonick, Alicia A. Caldwell and Kim Hefling contributed to this report.

Source: http://news.yahoo.com/shutdown-impact-national-parks-could-reopen-200337756.html
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First Photos of the Erik Buell Racing 1190RX

Yesterday we brought you the first detail photos of the Ducati 1199 Superleggera, Bologna’s ultra-exclusive superbike, and before that we showed you the magnesium, titanium, and carbon fiber parts that would comprise the Superleggera, and help the machine drop a rumored 40 lbs from its already anorexic body. Now, we have the first clear photo of the 2014 Ducati 1199 Superleggera, taken apparently at Ducati’s dealer meeting in New Orleans. Only 500 of these beasts will be built worldwide, and first dibs are going to Borgo Panigale’s best customers. Cost is said to be in the $65,000 range for US buyers, €60,000 for Europeans. Though the photos that leaked out yesterday teased a Corse-inspired paint scheme, this is our first look at the finished livery for the Superleggera.

The leaks from Ducati keep coming in, and now we have our first photos of the Ducati 1199 Panigale R Superleggera, or “Project 1201″ as Ducati is calling it for now, and its tasty details. Stripped of its carbon fiber fairings, we can see where all those magnesium, titanium, and carbon pieces reside on the Superleggera’s rolling chassis. Continuing our extensive coverage of this machine’s debut, Asphalt & Rubber has gotten its hands on 16 detail photos of the new Ducati Superleggera, and they are waiting for you after the jump.

Earlier today, I was thinking of writing a story that would be titled “The Four Obvious Bikes that BMW is about to Debut” or something like that. While that list would include the spied water-cooled BMW R1200RT, BMW S1000R, and BMW NineT machines, at the top of that list would be the BMW R1200GS Adventure, which is predictable extension of the new GS, which debuted last year. BMW, it would seem, has beaten me to the punch. Officially official, the 2014 BMW R1200GS Adventure has broken cover now, and is ready for you to ADV on until your heart is content.

A&R broke the news last week about the upcoming Ducati 1199 Panigale R Superleggera, and we have already seen spy photos of the Ducati Scrambler (said to be a 2015 model, if it gets the production nod), and a liquid-cooled Ducati Monster 1200. Turning our attention to the latter in that list, what you see above is a photo of what greeted Ducati dealers when Ducati North America debuted its 2014 line to them last week in New Orleans, and from the look of things, the machine in question appears to be a street-ready roadster. What we for now will call the 2014 Ducati Monster 1200, this new motorcycle features a water-cooled Testastretta 11° engine, and is supposed to be along the same vein as the Monster S4 and its progeny.

Ducati has gone to great lengths so that you won’t know this, but our sources have confirmed to us that in about a month’s time, the Bologna Brand will debut perhaps the most ostentatious machine ever to come from the Borgo Panigale factory, the Ducati 1199 Panigale R Superleggera. An ultra-exclusive version of the Ducati 1199 Panigale R, the Superleggera edition is exactly what its Italian name suggests, a super-light version of the Panigale R. It’s ok if you need to take a minute to readjust yourself in your chair before reading further — we’ll wait.

With the advent of cheap wearable cameras, the internet has become awash with road rage videos, which unsurprisingly sometimes feature motorcyclists. That brings us to our latest edition, where a large group of motorcyclists in New York are caught on film having an altercation with a Range Rover Sport. We come into the incident after it begins, with a pack of motorcycles enveloped around the SUV on the West Side Highway, and a couple riders already gesticulating with the driver, Alexian Lien. One motorcyclist pulls in front of the Range Rover, brake-checks the four-wheeler, and is subsequently rear-ended…things then spiral out of control from there.

At the EICMA show last year, BMW Motorrad announced that it would make another air-cooled model, in order to commemorate the 90 years that the German OEM has been producing two-wheelers. Expected to be the production version of the company’s LoRider concept, we got our first taste of what BMW had in store for us with the BMW Concept Ninety — which had its retro goodness co-developed with America’s own Roland Sands. Now seemingly ready for a true production model, BMW Motorrad has been caught testing the BMW NineT street bike inside the Lake Garda region in Italy. Obviously fitted with the 1,200cc air-cooled boxer twin that has made the GS and RT such steady steeds, the NineT uses classic motorcycle aesthetics, mated to classic BMW design pieces.

Rider aids like traction control and ABS continue to prove the notion that electronics are the new horsepower, and with the US debut of the KTM 1190 Adventure R just a couple months away, we learn that the hot new adventure-touring machine will debut the new Bosch Motorcycle Stability Control (MSC) system. An extension of the venerable Bosch 9+ME ABS package, whose dual-channel setup has become the benchmark for OEM-equipped ABS units, the Bosch MSC is the next iteration of that standard. Integrating the ability for riders to brake into corners with a reduced risk of low-sliding, the Bosch MSC system is the next evolution in braking with its anti-lowside technology.

Valentino Rossi is to back a Moto3 team showcasing Italian talent from next season. The Italian will work with Sky Italia, the broadcaster who will be taking over the broadcast rights for MotoGP from next season, to field a pair of riders including current FMI Italia rider Romano Fenati on KTM machines. Sky Italia will be the main sponsor, while Rossi’s VR46 clothing and merchandise brand will provide support and backing for the project.The confirmation that Rossi will back the Sky Moto3 team comes after weeks of intense speculation that the nine-times World Champion was preparing to get involved in Moto3. Rossi had denied reports that he would manage a team, a denial which is strictly true. Rossi’s involvement will be at a greater remove.

Since its concept debut at the 2012 INTERMOT show, details of the 2014 Suzuki V-Strom 1000 adventure-touring bike have slowly dribbled from the Japanese manufacturer’s lips. Giving us today a healthy dose of technical specifications and photos, Suzuki seems all but ready to debut its new V-Strom 1000. Featuring a 1,037cc v-twin engine, which makes a peak 99hp at 8,000 rpm and 76 lbs•ft at 4,000 rpm, Suzuki has added a traction control system (a first for Suzuki) and ABS into the mix as well. Once again, Suzuki TL1000S & Suzuki TL1000R owners will recognize the 90° v-twin engine beneath the V-Strom’s fairings, though Suzuki has bored the cylinders out by 2mm, brining them to a full 100mm bore.

Source: http://feedproxy.google.com/~r/AsphaltandRubber/~3/mZDJidAMsEo/
Tags: jim parsons   sofia vergara   Nokia   Charlie Manuel   Sean Sasser  

Eminem Releases "Rap God": Listen Here!

Delivering the healthy dose of egotism that is so prevalent in rap music, Eminem released his new tune, "Rap God" on Monday (October 14).

Sharing the exciting news on Twitter, Marshall Mathers tweeted, "Earlier than expected, #RAPGOD is here. It will be available on iTunes Midnight ET tonight."

On the track, which features rapid-fire rhymes from the 40-year-old rapper, he boasts, "I’m beginning to feel like a rap god, rap god / All my people from the front to the back nod, back nod," later adding, "Why be a king when you can be a god?"

On November 5th, Em's upcoming Album, The Marshall Mathers LP 2, hits stores and includes both "Rap God" and his first single, "Berzerk." In the meantime, check out the new tune below.

Source: http://celebrity-gossip.net/eminem/eminem-releases-rap-god-listen-here-942498
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Three U.S. Economists Win Nobel Prize

Americans Eugene Fama, Lars Peter Hansen and Robert Shiller won the Nobel prize for economics on Monday for developing new methods to study trends in asset markets.

The Royal Swedish Academy of Sciences said the three had laid the foundation of the current understanding of asset prices.

While it's hard to predict whether stock or bond prices will go up or down in the short term, it's possible to foresee movements over periods of three years or longer, the academy said.

"These findings, which might seem surprising and contradictory, were made and analyzed by this year's laureates," the academy said.

Fama, 74, and Hansen, 60, are associated with the University of Chicago. Shiller, 67, is a professor at Yale University.

American researchers have dominated the economics awards in recent years; the last time there was no American among the winners was in 1999.

The Nobel committees have now announced all six of the annual $1.2 million awards for 2013.

The economics award is not a Nobel Prize in the same sense as the medicine, chemistry, physics, literature and peace prizes, which were created by Swedish industrialist Alfred Nobel in 1895. Sweden's central bank added the economics prize in 1968 as a memorial to Nobel.

Source: http://www.npr.org/2013/10/14/233889206/three-u-s-economists-win-nobel-prize?ft=1&f=1001
Tags: Marquez vs Bradley   Mexico vs Panama   john lennon   miami dolphins   nfl scores  

Daily Roundup: BlackBerry Z30 review, Steam Controller hands-on, Google's new policy turns you into an ad and more!

You might say the day is never really done in consumer technology news. Your workday, however, hopefully draws to a close at some point. This is the Daily Roundup on Engadget, a quick peek back at the top headlines for the past 24 hours -- all handpicked by the editors here at the site. Click on through the break, and enjoy.

BlackBerry Z30 review

It's not the best time for BlackBerry right now. Between layoffs and quarterly loses, the company is certainly going through a rough patch. The Z30 -- BlackBerry's latest attempt at turning things around -- features a 5-inch Super AMOLED display (making it the biggest BB10 device yet), along with 2GB of RAM and a CPU clocked at 1.7GHz. The phone is undoubtedly a step in the right direction, but buggy software, a poor camera and an expensive price tag keep it off of our must-buy list. Read on for more.

See the Steam Controller in action right here

We've already seen Valve's Steam Controller in stills, but today we got the chance to watch the new device in action. The video above demos a number of games, including Portal 2 and Counter-Strike: Global Offensive. The former of those two titles employees the controller's dual touchpads as thumbsticks which looks to be a bit cumbersome. In the other game we saw the controller's ability for precision, but ultimately we'd like to get a better idea of using the controller in a more rigorous match. Click the link above for more details and a hands-on video.

If you use Google services, you could become an ad next month

Privacy in this day and age is becoming a topic of increasing contention, and Google's latest batch of fine print is certain to cause many users to bristle. In an updated Terms of Service agreement today, users' profiles will start showing up in ads across the web -- based on reviews, comments, +1s and follows you make through the company's services. We know what you're thinking: you want out. Luckily Google has provided such an option with the ability to opt-out. These changes are set to go live on November 11th, so head on over to that new agreement and do what you will. Head up for more.

Here's the retail packaging for PlayStation 4

Anxious to get your hands on the new PlayStation 4? Sony's trying to make the wait easier (or harder) for you by releasing a gallery of pictures showing the console's box and packaging. As you probably guessed the box is blue and white, while the DualShock 4 comes in classic black, "Wave Blue" and "Magma Red." For more details and pictures click the link above.

Source: http://www.engadget.com/2013/10/11/daily-roundup-blackberry-z30-review-steam-controller-hands-on/?ncid=rss_truncated
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